Bionanotechnology combines biology with nanotechnology to develop innovations that are particularly important in the biomedical sector. It integrates biological and technological components on the smallest scale, enabling advanced healthcare applications such as improved drug development and diagnostic methods. This technology holds the potential for significant societal and economic benefits by offering new treatments for diseases and contributing to sustainability and the energy transition. With its expertise, the Netherlands plays an important role in advancing bionanotechnology internationally.
The challenge
This technology field faces the challenge of integrating biological and technological building blocks, such as cells and sensors, into advanced systems. This integration is complex due to the fundamental differences between "hard" technological and "soft" biological materials. Developing production technologies capable of handling both is crucial. Challenges include creating smart biomembranes with embedded sensors for tissue engineering, scaling up the production of cells for local bioprinting, and designing biosensors capable of detecting diverse biological processes. These innovations require deep interaction between various technological and biological domains.
The approach
Bionanotechnology focuses on translating innovations from research institutions into practical biomedical applications. This strategy emphasizes two main objectives: supporting technology transfer to industry to develop prototypes and creating additional technological and biological building blocks to expand the functionality of these applications. By fostering collaboration between academia and industry, challenges such as integrating technical components and functionalizing sensors are addressed. The ultimate goal is to develop standardized protocols within the next decade that seamlessly integrate microsensors and microfluidics with biological systems.
The impact
Advancements in bionanotechnology contribute to significant improvements in the biomedical sector, such as accelerating drug development and opening new research opportunities for rare diseases. It also promises benefits in agrifood, sustainability, and the energy transition through innovative sensors and materials. With expertise in microfluidics and cell technology, the Netherlands is well-positioned to excel in the development of diagnostic devices like Organs-on-Chips. Furthermore, bionanotechnology offers potential for progress in production techniques and deeper insights into complex diseases, paving the way for breakthroughs in medical research and applications.